Sustainable development has become an important issue of concern to all walks of life nowadays. Although many universities have incorporated the concept into their sustainable development policies, there is still a lack of a comprehensive sustainability evaluation index system. In contrast, in recent years, the business community has become popular in terms of environmental, social and governance concepts (ESG) to measure sustainable performance. However, in the past, discussions on ESG-related issues were mostly focused on the field of business administration and finance, but there has been little research on applying ESG indicators to the field of higher education. This research collated relevant domestic and foreign literature and summarized the preliminary structure of ESG indicators applied to National Tsinghua University. After revising the indicators through expert validity questionnaires, a formal hierarchical structure of 21 indicators was constructed, and then the Analytic Hierarchy Process (AHP) was used to establish an evaluation model and select relevant stakeholders according to the four-helix model into industry, government, academia, and citizens to conduct an AHP questionnaire survey, and after analysis, concluded the importance of National Tsinghua University in ESG aspects and detailed indicators. The research results show that stakeholders believe that the governance (G) aspect of National Tsinghua University is the most important in the overall ESG, followed by the social (S) aspect, and the environment (E) aspect is the lowest; the overall index is based on teaching and Research resources are given utmost importance. The results of this study can provide implications from different aspects of the university as a reference direction for the legalization of higher education and the sustainable development of university affairs. In the future, appropriate methods can be further used to establish an ESG practical evaluation system suitable for universities, and then provide policy suggestions for various aspects of ESG.