西班牙人在菲律賓建立其帝國東亞的殖民地後，便透過貿易與天主教傳教士兩種 途徑與中國沿海地區展開交流，而後來發跡於福建的明鄭亦是在這樣的歷史背景下與西班牙 帝國建立關係。以往有關鄭氏家族與菲律賓關係的研究，由於相關中文史料的缺乏以及外文 史料的蒐求不易，以致到目前為止，所能瞭解的仍僅僅只是一些輪廓而已。本文藉由整理前 人的研究成果以及筆者近來所發現的一些有關鄭經的西班牙文新史料，先加以互相驗證並分 別就鄭芝龍、鄭成功、鄭經及鄭克塽四個時期與西班牙帝國所進行的貿易活動及其個人與天 主教的關係和態度進行討論，以此對兩者之間的各項關係，進行更深一層及完整的認知與理 解。

　　　　　After occupying the Philippines as a base for colonization in East Asia, the Spanish Empire began to establish contact with coastal China through trade and Catholic proselytism. The Cheng clan, which came to prominence in the coastal area of south China during the Ming dynasty, began to establish relations with the Spanish Empire at that time. Due to the scarcity of Chinese-language resources and the difficulty collecting data in other languages, until recently little was known about the factual interactions between the Cheng clan and the Philippines. The present article is based both on previous research findings and materials on the Cheng clan found by the author in the Archives of India in Seville, Spain. Through the examination of trade relations and religious interaction between the Cheng clan and the Spanish Empire over four generations (Cheng Chih-lung, Cheng Ch'eng-kung, Cheng Ching and Cheng K'o-shuang), the author attempts to present a detailed and comprehensive picture of the various aspects of this relationship.