This paper analyzes the contents of STEM-related curriculum standard documents of the United States, Ontario of Canada, Finland, South Korea, Singapore, United Kingdom, Victoria of Australia, France, and China. Through in depth understanding of the characteristics and trends of these countries in the integration of curriculum, horizontal integration and vertical integration are compared. The horizontal integration model of these countries mainly includes three types, which are the construction of the interdisciplinary conceptual system with the core concept, the interdisciplinary practice through project, and the expectation of students’ performance. The vertical integration model is either a model of vertical integration through core concepts and performance expectations, or a model of vertical integration through disciplinary core concepts and content requirements. Based on the analysis of the characteristics and trends of the national integration model, this paper puts forward some suggestions for the design of STEM related courses, in order to provide relevant curriculum design for our country’s strategy and reference.