The historical formation of the disciplines of the humanities contains four significant components that concern the relationship between modern humanistic knowledge and traditional religious knowledge or the knowledge of the classics,the relationship between humanities and natural sciences, the relationship between modern eastern and western civilizations,and the relationship between the formation of humanistic knowledge and cultural movements as well as the emergence of new cultural classes. With the development of globalization and regionalization, humanities in the modern world face some major challenges, which, in turn, challenge the formation of modern humanitistic disciplines.