本研究旨在探討運動前及運動中補充含抗氧化劑之飲料對體內抗氧化能力及肌肉損傷之影響。以15名健康男性為對象，在高強度(80％VO2max)、固定負荷之跑步耐力運動前一小時飲用500ml及運動中每15分鐘飲用150ml含抗氧化劑之飲料(A)或純水(w)直至力竭，在運動前、運動30分鐘、力竭點時，採集血液進行生化值之分析。結果發現，超氧化歧化酶(superoxide dismutase)活性及麩胱甘酶(glutathione)濃度變化兩組組間比較無顯著性差異。在脂質過氧化物MDA+4-HNE(malondialdehyde+4-hydroxynonenal)產生情形上，力竭時A組MDA+4-HNE增加之比率顯著低於W組(p<0.05)。肌肉損傷情形，運動力竭時A組血漿中磷酸肌酶(creatine kinase)及乳酸脫氫酶(lactate dehydrogenase)活性上升的幅度低於W組，但兩組問並無明顯之差異。由以上總結，運動前及運動中補充含抗氧化劑之飲料能有效降低脂質過氧化物的產生，而對於降低運動所造成之細胞損傷之情形仍需進一步探討。

The purpose of the study was to investigate the effects of supplementation containing antioxidants on oxidative stress and muscle damage in endurance exercise. Fifteen untrained healthy males (mean age 24.4± 2.4yr) were assigned to drink either on antioxidant beverage (A) or water (W) on two sessions separated by I week. The antioxidant beverage contained 0.2 mg vitamin E, 20 mg vitamin C, 0.12 mg n-carotene, 4.0 g fructose, 1.0 g glucose and 1.0 g sucrose per 100 ml. Subjects consumed 500m1 of A or W one hour before exercise and 150 ml every 15 mm during an 80% maximal 02 consumption (VO2max) treadmill exercise. The concentrations of biochemical parameters were measured pre-exercise, ex-30 mm, and exhaustion. The results indicated that no significant differences were observed between the two groups for superoxide dismutase (SOD) activity and glutathion (GSH) concentration. The malondialdehyde+4-hydroxynonenal (MDA+4-HNE) production at exhaustion in A group was significantly lower than W group. There was also no significant difference in creatine kinase (CK) and lactate dehydrogenase (LDH) activity for the two groups during exercise, eventhough the A group tend decreased the activity of CK. In conclusion, ingestion of antioxidant beverage before and during exercise might help to decrease lipid peroxidation.