In the process of instruction, it can often be found that students ignore the pursuit of professional knowledge because of their emphasis on innovation and creativity, and even over-stress imagination and inspiration, resulting in the so-called innovation only degraded into whimsical thinking, and even though there are new ideas, they cannot be substantiated out of insufficient knowledge. Therefore, this article address this issue in a claim that impact of knowledge accumulated on the expansion of personal experiences or the as well as the formation of cognitive architecture that supports innovation and substantiates imagination is huge. Although students may acknowledge the impact of knowledge on innovation, they still feel hard to experience it, which has much to do with the rigidity of the learning process and the submission to the authority of knowledge. As time goes by, they do not even give credit to their hard work. Therefore, in the course of instruction, more use or informal knowledge to verify formal knowledge, or through the differences of both to enable students to have doubts, to exercise their imagination, and to mobilize a variety of learned knowledge to find answers, which may perhaps change the rigid habit of thinking, and foster their innovation and enterprising spirits.