Accidental falls are highly prevalent, resulting in injury and increased medical expenditure. The accidental falling rate for acute psychiatric inpatients was 0.09%, much higher than 0.06% for all inpatients in Taichung Veterans General hospital. Drugs adverse effects and related limbs weaknesses were identified as major factors. The standard operation procedure (S.O.P.) and inpatients' awareness for falling prevention are inadequate. In order to prevent accidental falls, we modified the S.O. P. for falling prevention and education, improved the ward environment, conducted team discussion for medication adjustment, and provided psycho-education via group and individual approaches. After implementation of the program, the rate of falls was lowered to 0.04%. Although unstable psychotic symptoms and poor compliance of acute psychiatric inpatients are great challenges for medication adjustment, falling prevention, and nursing care, improving patients' security and quality of care remains an ultimate goal to achieve in the future.