In this study, we applied computer software ALOHA(Areal Locations of Hazardous Atmospheres) software, to simulation benzene and n-n-dimethyl storage tank leakage, simulate when occur fire and explosion consequence, to understand endanger regional and incident handling staff should be maintain safe distance. About apply ALOHA to analysis N-N-Dimethyl lead to pool fire, maybe ALOHA suppose that when the leakage after the spark, so leaking liquid N-N-Dimethyl liquid pool fi re formed in the anti-leak dike immediately, the greatest impact the range of about infl uence distance less than 150 m. The fi reball explosion simulation results, the workers in the orange zone will have the possible suffer second-degree burns, while the distance of the orange zone fi reball explosion about 1.2 km. About apply ALOHA to analysis Benzene lead to pool fi re, the greatest impact the range of about 500 m or so, no more than 600 m. The fi reball explosion simulation results, the workers in the orange zone will have the possible suffer second-degree burns, while the distance of the orange zone fi reball explosion about 2.6 km.