According to the development of the geographic information system, if we can wisely use the map platform searching for the number of communications and death of infectious diseases from the past to the present, understanding why the epidemic situation was so serious in certain areas and how the environment of diseases and areas affects them, it would be favorable for the public or scholars to do research and prevention. So far, the types of map platforms are multivariant and functions are complicated. We decided to establish a disease searching system based on Google Maps and Highmaps in order to compare the pros, cons and differences of these two platforms. From the results of the experiment, if the geographical coordinates of the location or query detailed location information such as mark the residential address for infectious disease cases, we must use Google Maps to be able to reach. On the other hand, Highmaps has more advantages on combining many types of statistical charts for analysis of infectious disease historical data. In the future, we hope it is possible to combine the advantages of these two map platforms into a professional map information platform that is user-friendly, more flexible, and has charting features.