A special clinic for psychosexual problems was established since 1995 in Kaohsiung. The new concept of sexual dysfunction and sex therapy as defined mainly in Master and Johnson, as well as Helen Kaplan formats has been adapted and applied to patients in the clinic. Besides, one set of instruments consists of two divided parts. The first part is the semistructured "Diagnostic Interview Schedule for Psychosexual Disorders", which is administered by face to face interview. The second part is a series of self-rating scales including Questionnaire of Sexual knowledge, Sexual Attitude, Sexual Response and Dyadic Communication Questionnaire covering General and Sexual Communication. These scales were developed for the evaluation of underlying contributing factors. During the time from Jan. 1995 to Apr. 1996, there were 128 case of sexual dysfunctions including 112 psychogenic ones. Fifteen cases (13.4%) were successfully treated, 4 cases (3.6%) failed, and the rest 75 cases (67%) refused or dropped out. The motivations of help-seeking are mainly oriented toward sexual function and fertility in male and marital crisis, and eurotic disorders in females, which implied biological-oriented of the former and psychosocial concerns of the latter, respectively. In general, "Infertility" is a significantly positive factor for continuity of sex therapy. Within 63 pair of married couples, 19 couples (30.2%) have comorbid marital problems which are mainly attributed to poor communication. In addition, the self-rating scale outcome of 44 patients with sexual dysfunction is compared with a normal control group (N=25), and it revealed a low score profile on Sexual knowledge in both groups and a significant difference in Sexual Attitude, Sexual Response and Sexual communication. The overall results indicated that the patient group was more conservative and traditionally oriented in terms of sexual attitude and experience, and also had inadequate sexual communication with partners. It should be the focus of sex therapy.