:::

詳目顯示

回上一頁
題名:五羥色胺系統對母性行為的調控及其機制
書刊名:心理科學進展
作者:陳磊磊聶莉娜李鈺程鵬李鳴高軍
出版日期:2017
卷期:2017(12)
頁次:2089-2098
主題關鍵詞:五羥色胺母性行為神經環路激素Serotonergic systemMaternal behaviorNeuronal circuitHormone
原始連結:連回原系統網址new window
相關次數:
  • 被引用次數被引用次數:期刊(0) 博士論文(0) 專書(0) 專書論文(0)
  • 排除自我引用排除自我引用:0
  • 共同引用共同引用:0
  • 點閱點閱:8
母性行為是一種復雜的本能社會行為,對子代的生存和發展具有重要意義。近幾十年來,嚙齒類動物母性行為的神經生物學機制研究方面取得了很大進展,但對母性行為的五羥色胺系統調控機制卻缺乏足夠重視。因此本文重點圍繞五羥色胺系統展開論述。首先簡要介紹了母性行為及其研究范式和基本神經環路機制,隨后我們重點闡述了五羥色胺系統調控母性行為的生理心理學、神經環路、神經受體、神經內分泌和分子調節機制方面的研究進展。最后指出未來的研究需要加強對五羥色胺系統調控母性行為的神經環路機制、五羥色胺系統和其他神經遞質(比如多巴胺和催產素)系統的交互作用調控機制的研究。
Maternal behavior is a complex social behavior which is essential for the survival and development of the offspring. Many progresses have been made in recent decades on the neurobiological mechanisms of maternal behavior, especially in rodents. The present study focuses on the serotonin system, a major neurotransmitter system that has not received enough attention in this field. We first provide a brief overview of rat maternal behavior and the basic functions of the serotonin system. Next, we review recent work on the role of serotonin in the mediation of maternal behavior, focusing on the specific receptor subtypes. We examine evidence concerning the physio-psychological and neuroanatomical, neurochemical and neuroendocrine mechanisms of serotonin and the related gene regulation. Finally, we point out several future research directions, one of which concerns the potential interactions between serotonin and other neurochemicals, such as dopamine and oxytocin in the regulation of maternal behavior.
期刊論文
1.Cools, R.、Roberts, A. C.、Robbins, T. W.(2008)。Serotoninergic regulation of emotional and behavioural control processes。Trends in cognitive sciences,12(1),31-40。  new window
2.Lawson, A.、Murphy, K. E.、Sloan, E.、Uleryk, E.、Dalfen, A.(2015)。The relationship between sleep and postpartum mental disorders: A systematic review。Journal of Affective Disorders,176,65-77。  new window
3.Angoa-Pérez, M.、Kane, M. J.、Sykes, C. E.、Perrine, S. A.、Church, M. W.、Kuhn, D. M.(2014)。Brain serotonin determines maternal behavior and offspring survival。Genes, Brain and Behavior,13,579-591。  new window
4.Alenina, N.、Kikic, D.、Todiras, M.、Mosienko, V.、Qadri, F.、Plehm, R.、Bader, M.(2009)。Growth retardation and altered autonomic control in mice lacking brain serotonin。Proceedings of the National Academy of Sciences of the United States of America,106,10332-10337。  new window
5.Agrati, D.、Ferreño, M.、Marin, G.、Uriarte, N.、Zuluaga, M. J.、Fernández-Guasti, A.、Ferreira, A.(2016)。Previous and recent maternal experiences modulate pups' incentive value relative to a male without affecting maternal behavior in postpartum estrous rats。Journal of Physiology-Paris,110,140-148。  new window
6.Agrati, D.、Fernández-Guasti, A.、Ferreira, A.(2008)。The reproductive stage and experience of sexually receptive mothers alter their preference for pups or males。Behavioral Neuroscience,122,998-1004。  new window
7.Barofsky, A. L.、Taylor, J.、Tizabi, Y.、Kumar, R.、Jones-Quartey, K.(1983)。Specific neurotoxin lesions of median raphe serotonergic neurons disrupt maternal behavior in the lactating rat。Endocrinology,113,1884-1893。  new window
8.Avinun, R.、Ebstein, R. P.、Knafo, A.(2012)。Human maternal behaviour is associated with arginine vasopressin receptor 1A gene。Biology Letters,8,894-896。  new window
9.Angoa-Pérez, M.、Kuhn, D. M.(2015)。Neuronal serotonin in the regulation of maternal behavior in rodents。Neurotransmitter,2,e615。  new window
10.Barofsky, A. L.、Taylor, J.、Massari, V. J.(1983)。Dorsal raphe-hypothalamic projections provide the stimulatory serotonergic input to suckling-induced prolactin release。Endocrinology,113,1894-1903。  new window
11.Bagdy, G.(1995)。Role of the hypothalamic paraventricular nucleus in 5-HT1A, 5-HT2A and 5-HT2C receptor-mediated oxytocin, prolactin and ACTH/corticosterone responses。Behavioural Brain Research,73,277-280。  new window
12.Bosch, O. J.、Neumann, I. D.(2010)。Vasopressin released within the central amygdala promotes maternal aggression。European Journal of Neuroscience,31,883-891。  new window
13.Bridges, R. S.(2015)。Neuroendocrine regulation of maternal behavior。Frontiers in Neuroendocrinology,36,178-196。  new window
14.Bridges, R. S.、Mann, P. E.、Coppeta, J. S.(1999)。Hypothalamic involvement in the regulation of maternal behaviour in the rat: Inhibitory roles for the ventromedial hypothalamus and the dorsal/anterior hypothalamic areas。Journal of Neuroendocrinology,11,259-266。  new window
15.Brummelte, S.、Galea, L. A. M.(2016)。Postpartum depression: Etiology, treatment and consequences for maternal care。Hormones and Behavior,77,153-166。  new window
16.Champagne, D. L.、Bagot, R. C.、van Hasselt, F.、Ramakers, G.、Meaney, M. J.、de Kloet, E. R.、Krugers, H.(2008)。Maternal care and hippocampal plasticity: Evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress。Journal of Neuroscience,28,6037-6045。  new window
17.Chen, W. J.、Zhang, Q.、Su, W. X.、Zhang, H. R.、Yang, Y.、Qiao, J.、Li, M.(2014)。Effects of 5-hydroxytryptamine 2C receptor agonist MK212 and 2A receptor antagonist MDL100907 on maternal behavior in postpartum female rats。Pharmacology Biochemistry and Behavior,117,25-33。  new window
18.Cleveland, A.、Westergaard, G. C.、Trenkle, M. K.、Higley, J. D.(2004)。Physiological predictors of reproductive outcome and mother-infant behaviors in captive rhesus macaque females (Macaca mulatta)。Neuropsychopharmacology,29,901-910。  new window
19.Claessens, S. E. F.、Daskalakis, N. P.、van der Veen, R.、Oitzl, M. S.、de Kloet, E. R.、Champagne, D. L.(2011)。Development of individual differences in stress responsiveness: An overview of factors mediating the outcome of early life experiences。Psychopharmacology,214,141-154。  new window
20.Dulac, C.、O'Connell, L. A.、Wu, Z.(2014)。Neural control of maternal and paternal behaviors。Science,345,765-770。  new window
21.De Almeida, R. M. M.、Giovenardi, M.、Silva, S. P. D.、Oliveira, V. P.、Stein, D. J.(2006)。The effect of 5-HT2a/2c receptor agonist microinjected into central amygdaloid nucleus and median preoptic area on maternal aggressive behavior in rats。Revista Brasileira de Psiquiatria,28,130-134。  new window
22.Corona, R.、Lévy, F.(2015)。Chemical olfactory signals and parenthood in mammals。Hormones and Behavior,68,77-90。  new window
23.Cramer, C. P.、Thiels, E.、Alberts, J. R.(1990)。Weaning in rats: I. Maternal behavior。Developmental Psychobiology,23,479-493。  new window
24.Diamantopoulou, A.、Raftogianni, A.、Stamatakis, A.、Alikaridis, F.、Oitzl, M. S.、Stylianopoulou, F.(2012)。Denial of reward in the neonate shapes sociability and serotonergic activity in the adult rat。PLoS One,7,e33793。  new window
25.Fleming, A.(1986)。Psychobiology of rat maternal behavior: How and where hormones act to promote maternal behavior at parturition。Annals of the New York Academy of Sciences,474,234-251。  new window
26.Ehret, G.(2005)。Infant rodent ultrasounds-a gate to the understanding of sound communication。Behavior Genetics,35,19-29。  new window
27.Fleming, A. S.、Corter, C.(1988)。Factors influencing maternal responsiveness in humans: Usefulness of an animal model。Psychoneuroendocrinology,13,189-212。  new window
28.Fleming, A. S.、Rosenblatt, J. S.(1974)。Maternal behavior in the virgin and lactating rat。Journal of Comparative and Physiological Psychology,86,957-972。  new window
29.Galef, B. G.(1981)。Preference for natural odors in rat pups: Implications of a failure to replicate。Physiology & Behavior,26,783-786。  new window
30.Gaub, S.、Ehret, G.(2005)。Grouping in auditory temporal perception and vocal production is mutually adapted: The case of wriggling calls of mice。Journal of Comparative Physiology A,191,1131-1135。  new window
31.Girirajan, S.、Elsea, S. H.(2009)。Abnormal maternal behavior, altered sociability, and impaired serotonin metabolism in Rai1-transgenic mice。Mammalian Genome,20,247-255。  new window
32.González-Mariscal, G.、Gallegos, J. A.(2014)。The maintenance and termination of maternal behavior in rabbits: Involvement of suckling and progesterone。Physiology & Behavior,124,72-76。  new window
33.Ito, H.、Shimogawa, Y.、Kohagura, D.、Moriizumi, T.、Yamanouchi, K.(2014)。Inhibitory role of the serotonergic system on estrogen receptor α expression in the female rat hypothalamus。Neuroscience Letters,583,194-198。  new window
34.Hyde, J. F.(1992)。Effects of phencyclidine on 5-hydroxytryptophan- and suckling-induced prolactin release。Brain Research,573,204-208。  new window
35.Hudson, R.、Cruz, Y.、Lucio, A.、Ninomiya, J.、Martínez-Gómez, M.(1999)。Temporal and behavioral patterning of parturition in rabbits and rats。Physiology & Behavior,66,599-604。  new window
36.Heiming, R. S.、Mönning, A.、Jansen, F.、Kloke, V.、Lesch, K. P.、Sachser, N.(2013)。To attack, or not to attack? The role of serotonin transporter genotype in the display of maternal aggression。Behavioural Brain Research,242,135-141。  new window
37.Gouvêa, T. S.、Morimoto, H. K.、de Faria, M. J. S. S.、Moreira, E. G.、Gerardin, D. C. C.(2008)。Maternal exposure to the antidepressant fluoxetine impairs sexual motivation in adult male mice。Pharmacology Biochemistry and Behavior,90,416-419。  new window
38.Lerch-Haner, J. K.、Frierson, D.、Crawford, L. K.、Beck, S. G.、Deneris, E. S.(2008)。Serotonergic transcriptional programming determines maternal behavior and offspring survival。Nature Neuroscience,11,1001-1003。  new window
39.Keer, S. E.、Stern, J. M.(1999)。Dopamine receptor blockade in the nucleus accumbens inhibits maternal retrieval and licking, but enhances nursing behavior in lactating rats。Physiology & Behavior,67,659-669。  new window
40.Jørgensen, H.、Riis, M.、Knigge, U.、Kjær, A.、Warberg, J.(2003)。Serotonin receptors involved in vasopressin and oxytocin secretion。Journal of Neuroendocrinology,15,242-249。  new window
41.Kaffman, A.、Meaney, M. J.(2007)。Neurodevelopmental sequelae of postnatal maternal care in rodents: Clinical and research implications of molecular insights。Journal of Child Psychology and Psychiatry,48,224-244。  new window
42.Li, M.(2015)。Antipsychotic drugs on maternal behavior in rats。Behavioural Pharmacology,26,616-626。  new window
43.Li, M.、Budin, R.、Fleming, A. S.、Kapur, S.(2005)。Effects of chronic typical and atypical antipsychotic drug treatment on maternal behavior in rats。Schizophrenia Research,75,325-336。  new window
44.Li, M.、Davidson, P.、Budin, R.、Kapur, S.、Fleming, A. S.(2004)。Effects of typical and atypical antipsychotic drugs on maternal behavior in postpartum female rats。Schizophrenia Research,70,69-80。  new window
45.Lonstein, J. S.、Lévy, F.、Fleming, A. S.(2015)。Common and divergent psychobiological mechanisms underlying maternal behaviors in non-human and human mammals。Hormones and Behavior,73,156-185。  new window
46.Lonstein, J. S.、Simmons, D. A.、Stern, J. M.(1998)。Functions of the caudal periaqueductal gray in lactating rats: Kyphosis, lordosis, maternal aggression, and fearfulness。Behavioral Neuroscience,112,1502-1518。  new window
47.Lonstein, J. S.、Stern, J. M.(1997)。Role of the midbrain periaqueductal gray in maternal nurturance and aggression: c-fos and electrolytic lesion studies in lactating rats。Journal of Neuroscience,17,3364-3378。  new window
48.Lonstein, J. S.、Stern, J. M.(1998)。Site and behavioral specificity of periaqueductal gray lesions on postpartum sexual, maternal, and aggressive behaviors in rats。Brain Research,804,21-35。  new window
49.Marlin, B. J.、Mitre, M.、D'amour, J. A.、Chao, M. V.、Froemke, R. C.(2015)。Oxytocin enables maternal behaviour by balancing cortical inhibition。Nature,520,499-504。  new window
50.Melo, A. I.、Pérez-Ledezma, M.、Clapp, C.、Arnold, E.、Rivera, J. C.、Alison, S. F.(2009)。Effects of prolactin deficiency during the early postnatal period on the development of maternal behavior in female rats: Mother's milk makes the difference。Hormones and Behavior,56,281-291。  new window
51.Marcinkiewcz, C. A.、Mazzone, C. M.、D'Agostino, G.、Halladay, L. R.、Hardaway, J. A.、DiBerto, J. F.、Kash, T. L.(2016)。Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala。Nature,537,97-101。  new window
52.Numan, M.(2006)。Hypothalamic neural circuits regulating maternal responsiveness toward infants。Behavioral and Cognitive Neuroscience Reviews,5,163-190。  new window
53.Numan, M.(2007)。Motivational systems and the neural circuitry of maternal behavior in the rat。Developmental Psychobiology,49,12-21。  new window
54.Numan, M.、Bress, J. A.、Ranker, L. R.、Gary, A. J.、DeNicola, A. L.、Bettis, J. K.、Knapp, S. E.(2010)。The importance of the basolateral/basomedial amygdala for goal-directed maternal responses in postpartum rats。Behavioural Brain Research,214,368-376。  new window
55.Zhao, C.、Li, M.(2010)。C-Fos identification of neuroanatomical sites associated with haloperidol and clozapine disruption of maternal behavior in the rat。Neuroscience,166,1043-1055。  new window
56.Zhou, L.、Liu, M. Z.、Li, Q.、Deng, J.、Mu, D.、Sun, Y. G.(2017)。Organization of functional long-range circuits controlling the activity of serotonergic neurons in the dorsal raphe nucleus。Cell Reports,18,3018-3032。  new window
57.Yang, Y.、Qin, J. X.、Chen, W. H.、Sui, N.、Chen, H.、Li, M.(2015)。Behavioral and pharmacological investigation of anxiety and maternal responsiveness of postpartum female rats in a pup elevated plus maze。Behavioural Brain Research,292,414-427。  new window
58.Svirsky, N.、Levy, S.、Avitsur, R.(2016)。Prenatal exposure to selective serotonin reuptake inhibitors (SSRI) increases aggression and modulates maternal behavior in offspring mice。Developmental Psychobiology,58,71-82。  new window
59.Uphouse, L.(2014)。Pharmacology of serotonin and female sexual behavior。Pharmacology Biochemistry and Behavior,121,31-42。  new window
60.Wansaw, M. P.、Pereira, M.、Morrell, J. I.(2008)。Characterization of maternal motivation in the lactating rat: Contrasts between early and late postpartum responses。Hormones and Behavior,54,294-301。  new window
61.Wu, R. Y.、Gao, J.、Chou, S.、Davis, C.、Li, M.(2016)。Behavioral, pharmacological and neuroanatomical analysis of serotonin 2C receptor agonism on maternal behavior in rats。Psychoneuroendocrinology,73,252-262。  new window
62.Stolzenberg, D. S.、Champagne, F. A.(2016)。Hormonal and non-hormonal bases of maternal behavior: The role of experience and epigenetic mechanisms。Hormones and Behavior,77,204-210。  new window
63.Stern, J. M.、Johnson, S. K.(1990)。Ventral somatosensory determinants of nursing behavior in Norway rats. I. Effects of variations in the quality and quantity of pup stimuli。Physiology & Behavior,47,993-1011。  new window
64.Stern, J. M.(1996)。Somatosensation and maternal care in norway rats。Advances in the Study of Behavior,25,243-294。  new window
65.Stamatakis, A.、Kalpachidou, T.、Raftogianni, A.、Zografou, E.、Tzanou, A.、Pondiki, S.、Stylianopoulou, F.(2015)。Rat dams exposed repeatedly to a daily brief separation from the pups exhibit increased maternal behavior, decreased anxiety and altered levels of receptors for estrogens (ERα, ERβ), oxytocin and serotonin (5-HT1A) in their brain。Psychoneuroendocrinology,52,212-228。  new window
66.Stern, J. M.、Lonstein, J. S.(1996)。Nursing behavior in rats is impaired in a small nestbox and with hyperthermic pups。Developmental Psychobiology,29,101-122。  new window
67.Stamatakis, A.、Diamantopoulou, A.、Panagiotaropoulos, T.、Raftogianni, A.、Stylianopoulou, F.(2014)。A novel model of early experiences involving neonatal learning of a T-maze using maternal contact as a reward or its denial as an event of mild emotional adversity。Developmental Psychobiology,56,1651-1660。  new window
68.Sekiyama, T.、Nakatani, Y.、Yu, X. J.、Seki, Y.、Sato-Suzuki, I.、Arita, H.(2013)。Increased blood serotonin concentrations are correlated with reduced tension/anxiety in healthy postpartum lactating women。Psychiatry Research,209,560-565。  new window
69.Snoeren, E. M. S.、Veening, J. G.、Olivier, B.、Oosting, R. S.(2014)。Serotonin 1A receptors and sexual behavior in male rats: A review。Pharmacology Biochemistry and Behavior,121,102-114。  new window
70.Sheehan, T.、Paul, M.、Amaral, E.、Numan, M. J.、Numan, M.(2001)。Evidence that the medial amygdala projects to the anterior/ventromedial hypothalamic nuclei to inhibit maternal behavior in rats。Neuroscience,106,341-356。  new window
71.Sheehan, T. P.、Numan, M.(1997)。Microinjection of the tachykinin neuropeptide K into the ventromedial hypothalamus disrupts the hormonal onset of maternal behavior in female rats。Journal of Neuroendocrinology,9,677-687。  new window
72.Reisbick, S.、Rosenblatt, J. S.、Mayer, A. D.(1975)。Decline of maternal behavior in the virgin and lactating rat。Journal of Comparative and Physiological Psychology,89,722-732。  new window
73.Pfaff, D.、Waters, E.、Khan, Q.、Zhang, X. T.、Numan, M.(2011)。Minireview: Estrogen receptor-initiated mechanisms causal to mammalian reproductive behaviors。Endocrinology,152,1209-1217。  new window
74.Pereira, M.、Morrell, J. I.(2011)。Functional mapping of the neural circuitry of rat maternal motivation: Effects of site-specific transient neural inactivation。Journal of Neuroendocrinology,23,1020-1035。  new window
75.Saltzman, W.、Maestripieri, D.(2011)。The neuroendocrinology of primate maternal behavior。Progress in Neuro-Psychopharmacology and Biological Psychiatry,35,1192-1204。  new window
76.Sawano, E.、Doi, H.、Nagai, T.、Ikeda, S.、Shinohara, K.(2017)。Interactive effects of 5-HTTLPR genotype and rearing environment on affective attitude towards own infant in Japanese mothers。Behavioural Brain Research,325,173-180。  new window
77.Pereira, M.、Ferreira, A.(2006)。Demanding pups improve maternal behavioral impairments in sensitized and haloperidol-treated lactating female rats。Behavioural Brain Research,175,139-148。  new window
78.Pereira, M.、Morrell, J. I.(2010)。The medial preoptic area is necessary for motivated choice of pup- over cocaineassociated environments by early postpartum rats。Neuroscience,167,216-231。  new window
79.Olivier, B.(2015)。Serotonin: A never-ending story。European Journal of Pharmacology,753,2-18。  new window
80.Numan, M.、Stolzenberg, D. S.(2009)。Medial preoptic area interactions with dopamine neural systems in the control of the onset and maintenance of maternal behavior in rats。Frontiers in Neuroendocrinology,30,46-64。  new window
81.Olazábal, D. E.、Pereira, M.、Agrati, D.、Ferreira, A.、Fleming, A. S.、González-Mariscal, G.、Numan, M.(2013)。Flexibility and adaptation of the neural substrate that supports maternal behavior in mammals。Neuroscience & Biobehavioral Reviews,37,1875-1892。  new window
82.Numan, M.(1988)。Neural basis of maternal behavior in the rat。Psychoneuroendocrinology,13,47-62。  new window
圖書
1.Carlson, N. R.(2005)。Foundations of physiological psychology。Boston:Allyn and Bacon。  new window
2.Numan, M.、Insel, T. R.(2003)。The neurobiology of parental behavior。New York:Springer。  new window
圖書論文
1.Fleming, A. S.、Blass, E. M.(1994)。Psychobiology of the early mother-young relationship。Causal mechanisms of behavioural development。Cambridge:Cambridge University Press。  new window
2.Fleming, A. S.、Li, M.(2002)。Psychobiology of maternal behavior and its early determinants in nonhuman animals。Handbook of parenting: biology and ecology of parenting。Hillsdale:Lawrence Erlbaum Associates。  new window
 
 
 
 
第一頁 上一頁 下一頁 最後一頁 top