The purpose of this study is to analyze composite reliability, convergent validity and discriminant validity of the questionnaire of optimistic intelligence quotient. A total of 466 college students were recuited and they completed the measures in terms of the questionnaires of optimistic intelligence quotient, life satisfaction and resilience. The nonparametric Bootstrap method was used to explore the effect of optimistic intelligence quotient on life satisfaction, especially the mediating role of resilience between optimistic intelligence quotient and life satisfaction. The results showed that: 1) the reliability and validity of the questionnaire of optimistic intelligence quotient is pretty good; 2) optimistic intelligence quotient and resilience was significantly correlated with life satisfaction; 3) resilience plays a mediating role in the relationship between optimistic intelligence quotient and life satisfaction.