This case study was to evaluate the effects of applying behavioral change strategy and self-efficacy elevation of facilitating the rehabilitation of an amputation patient from bed to walk. The subject was a female diabetic patient whose left leg was amputated one year ago. Data was collected through telephone interview and home visit from March to May of 2001. After initial assessment, lacking motivation influenced her refusing to wear prosthetic and execute rehabilitation. The intervention process was designed as three stages. The first preparation stage was a stimulation control strategy for promoting motivation. The second stage was an action stage in which correct exercises were promoted and executed. Education about wearing prosthetic properly was also given at his stage by providing pictures and opportunity of practicing. Behavioral modeling and psychological supports were provided in the process. The third stage was the maintenance period in which education and assistance were applied to help the patient in managing pain and releasing discomfort. Family's participation was an important support factor in this stage. After the intervention, the patient decided to contact the prosthetic company and perform rehabilitation. This case study could provide a reference for nurse in caring similar patients.