Though the change and development of a region are related to nature factors, people who lived there will be more closely related to. The result of human and natural interaction may form different spatial structure pattern and appear regional aspect in different times and conditions. Through spatial process will present a different picture of the regional aspect in different times. The changes of the times always leave transition tracks on the old map. In this study, we will research the old map to draw a picture of the change and development of Yanhang region in Yong-kang, Tainan. Yan-hang region in Yong-kang, Tainan was a place along the seashore of ancient Tai-jiang coastal lagoon in southwest Taiwan. During the Dutch governed Era, the sphere of hunting activities of the Siraya people were changed farms or villages of Han people. In the early stage of Qing Dynasty, because Yan-hang being near the seashore, plenty of sunshine and convenient transportation promoted the Yan-hang regional salt business. When the salt business rose, the scale of Yan-hang village was expanding, because Tai-jiang coastal lagoon became raised land and the salt business declined in the middle stage of Qing Dynasty, Yan-hang was declining. Since the salt business declined, from the late stage of Qing Dynasty through 1940s, Yan-hang village had became a sugarcane planted village like the other inland villages in southwest Taiwan. The old Yan-hang village had been destroyed by Hsin-hwua earthquake in1946. The new Yan-hang village was constructed along the North-south Highway. Because the Chungshan free way, one of Ten Major Construction Projects in 1790, through east Yan-hang, the developmental direction of Yan-hang has been changed again. Yong-kang urban developmental project, Yan-hang has been reasonably divided into two sections, the industrial district and the residential district. Since Southern Science Industrial Park established in the late 1990s, and Yan-hang region is situated between Tainan city and Southern Science Industrial Park, Yanhang region get a rush development in residence, communication, industry and commerce.