The “Special Education Curriculum Guidelines” is revised by Ministry of Education, so the special education curriculum in vocational high school meets a lot of challenges. Therefore, we must change the type of special education curriculum to respond accordingly to the “Special Education Curriculum Guidelines”. The program integrates some subjects of “Animal Husbandry” and “Horticulture” to develop school-based characteristic for special education curriculum in vocational high school. The course program is based on the extension of self and peer and community relationships which are the basis for the development of interpersonal interaction. The implementation process found that most students can take advantage of the knowledge disciplines to solve the problems of life and maintain a high motivation to learn, which helps unite the class feelings and improve peer relationships.