The aim of this study is to confirm various factors, mainly by applying literature review and collection together with the Fuzzy Delphi Method, FDM. Then the Analytical Hierarchy Process, AHP is successively put in use to firmly establish the weight and consistency of the factors, which accordingly assists with the development of a more objective and precise assessment scale of fire prevention management for the reuse of historic buildings and monuments. Furthermore, to verify the importance of fire prevention measures adopted during 2017 National Museum of History disaster prevention drill in accordance with the acquired weight data. The conclusion of the research, through the analysis of FDM and AHP, the top five that experts and scholars place importance on are "daily fire prevention management and facility inspections", " fire safety management law system", "fire resistant material design", "regular rescue education /drills", and "disaster prevention measures under construction" in terms of the key indicators of fire prevention management for the reuse of historic buildings and monuments. All of these are in line with the core concept of protecting lives and safeguarding assets, starting from offering an environment without fire safety concerns for places like historic buildings and monuments.