Objectives: The prevalence of end-stage renal disease (ESRD) in Taiwan is the highest in the world. The high medical utilization by these patients has become a major burden on the healthcare system. In order to prevent and treat the disease, the Chronic Kidney Disease (CKD) care program which encourages patients to revisit regularly was launched in 2003; however, the outcome of regular visits has rarely been evaluated. In this study, we explored possible factors which may have influenced regular revisits by CKD patients as well as the clinical benefits of such behaviors.Methods: A total of 876 patients who joined the CKD care program from 2006 to 2009 at a medical center in Central Taiwan were retrospectively examined in terms of their basic characteristics, revisits and clinical progress.Results: Factors which contributed to regular revisits by patients with CKD included the stage of CKD, age, and follow-up period. Significant differences in the glomerular filtration rate (GFR) and serum creatinine level (Cr) were also found. For patients who revisited regularly, the rate of descending speed of their GFR was slower than that of those who did not and the Cr values of patients who were not followed-up periodically rose more rapidly.Conclusion: Regular revisits are beneficial for patients with CKD in order to effectively control GFR and Cr and delay the progression of disease.