本研究目的在探討單次不同阻力運動搭配不同加壓負荷對運動後代謝壓力與合成激素反應的影響。本研究招募15名健康男性，依對抗平衡次序原則分為：一、高強度阻力（70% 1 RM [repetition maximum]）；二、低強度阻力（40% 1 RM）；三、高強度阻力／低加壓（70% 1 RM + 70% SBP [systolic blood pressure]）；四、低強度阻力／高加壓（40% 1 RM+130% SBP）與五、低強度阻力／低加壓（40% 1 RM+70% SBP），間隔為五日。採雙腿斜坐推蹬方式（5組、12次），運動時加壓於雙腿大腿近端。比較運動前、運動後立即、15、30、60分鐘時，血清生長激素與睪固酮、乳酸與自覺努力程度之差異；並比較運動前與運動後60分鐘對肌力之影響。研究結果顯示：高強度阻力／低加壓的模式在運動後有較高的生長激素且持續至運動後30分鐘；相較於低強度阻力下的各種模式，高強度阻力／低加壓的模式在運動後立即有較高的睪固酮濃度，且能在運動後引起較高的壓力反應（乳酸與RPE值）並降低最大等長肌力表現，以及增加肌纖維徵召。本研究結論：高強度阻力運動搭配低加壓壓力的運動模式可顯著提高體內代謝壓力，同時可刺激更多生長激素與睪固酮分泌，對肌肉組織合成作用具有正面效益。

The purpose of this study was to investigate the effects of different resistance loads (70% and 40% 1 RM [repetition maximum]) combined with different occlusion pressures (130% and 70% SBP [systolic blood pressure]) on metabolic stress and anabolic hormonal response after exercise. Fifteen healthy males voluntarily participated in this study. A counter-balance order experimental design was used in this investigation. On the experiment day, each subject performed a single bout of bilateral leg extension (5 sets, 12 repetitions with 1 min rest for each set) under the following five experimental conditions: (1) high intensity resistance exercise (HR, 70% 1 RM), (2) low intensity resistance exercise (LR, 40% 1 RM), (3) HR with low occlusion pressure (HRLO, 70% 1 RM + 70% SBP), (4) LR with high occlusion pressure (LRHO, 40% 1 RM+130% SBP), and (5) LR with low occlusion pressure (LRLO, 40% 1 RM+70% SBP). Blood biomarkers (i.e. hormones and lactate) were measured at prior to exercise (pre), and 0, 15, 30, 60 min after (post) exercise. The maximal isometric strength and electromyography of vastus lateralis were compared at pre and post-60. Results indicated that the GH of HRLO was higher at post-0, post-15 and post-30 than that at pre-exercise. The testosterone of HRLO was higher at post compared to LRHO, LRLO and LR. Furthermore, HRLO induced greater metabolic and physiological stress responses (LA and RPE) and a greater decline of muscular strength with more muscle fiber recruitment. We concluded that high intensity resistance exercise combined with low occlusion pressure would elevate metabolic stress and reduce maximal strength performance, thereby stimulating higher GH and testosterone responses. Our results thus suggest that this exercise model would have the positive benefits on muscle anabolic effect.