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題名:
麩醯胺酸補充劑對有氧舞蹈後一氧化氮與同半胱胺酸的影響
書刊名:
大專體育學刊
作者:
唐存愷
/
傅正思
/
何應志
/
陳文詮
/
陳聰毅
/
蔡佈曦
作者(外文):
Tang, Tswen-kei
/
Fu, Cheng-sze
/
Ho, Ying-chih
/
Chen, Wen-chyuan
/
Chen, Tsung-i
/
Tsai, Pu-hsi
出版日期:
2017
卷期:
19:1
頁次:
頁87-98
主題關鍵詞:
耐力運動
;
心血管健康
;
血糖
;
Endurance exercise
;
Cardiovascular health
;
Blood glucose
原始連結:
連回原系統網址
相關次數:
被引用次數:期刊(0) 博士論文(0) 專書(0) 專書論文(0)
排除自我引用:0
共同引用:0
點閱:40
麩醯胺酸對心血管健康的影響,是因為麩醯胺酸與精胺酸和一氧化氮生成有關,本研究目的在探討補充麩醯胺酸對未受運動訓練的女學生,從事有氧舞蹈後對恢復期血中一氧化氮 (nitric oxide, NO) 與同半胱胺酸的影響。以14 位健康的女子大學生為對象,隨機分成兩組分別服用補充劑,一組補充安慰劑,一組補充L- 麩醯胺酸,補充劑量皆為每公斤體重0.1 公克,然後進行單次有氧舞蹈運動,連續運動2 小時,運動強度為55 ~ 75% 最大心跳率。每位受試者在運動前及運動後0、1、2 小時,採血以測量一氧化氮 (NOx, NO_2^- +NO_3^-)、同半胱胺酸、血糖、胰島素、高密度脂蛋白膽固醇 (high-density lipoprotein cholesterol, HDL-C)、低密度脂蛋白膽固醇 (low-density lipoprotein cholesterol, LDL-C)、三酸甘油酯及總膽固醇。研究結果顯示:運動後血中一氧化氮、胰島素、HDL-C、LDL-C、三酸甘油酯及總膽固醇在兩組間並沒有顯著差異。而補充麩醯胺酸組會增加運動後血中同半胱胺酸及葡萄糖濃度。因此麩醯胺酸可能可以幫助增加運動後恢復期同半胱胺酸及血糖。而目前並沒有足夠證據顯示補充麩醯胺酸能增加耐力運動恢復期的一氧化氮。本研究結論為單次補充麩醯胺酸並不能增加耐力運動2 小時恢復期血中一氧化氮含量,且沒有改善心血管健康指標的效果。
以文找文
The L-glutamine has been studied in cardiovascular health, because of its association with the L-arginine- NO cascade. This study aimed to investigate the effects of L-glutamine supplementation on acute plasma nitric oxide (NO) and homocysteine responses during recovery after aerobic dancing in untrained female students. Fourteen healthy female university students were randomly divided into two groups and received either placebo or L-glutamine at 0.1 g/kg-wt. Then the students were performed a single bout of aerobic dancing at an estimated speed corresponding to the 55 ~ 75% HRmax for 2 hours. Blood samples from each student were collected before exercise, and 0, 1 and 2 hours after exercise. The concentrations of NOx (NO_2^- + NO_3^-), homocysteine, glucose, insulin, HDL-C (high-density lipoprotein cholesterol), LDL-C (low-density lipoprotein cholesterol), triglycerol, and total cholesterol in blood were examined. The results showed that no differences in the levels of NOx, insulin, HDL-C, LDL-C, triglycerol, and total cholesterol between the groups were observed at any time points. However, the concentrations of homocysteine and glucose were significantly higher in the glutamine group compared to that in the placebo group at 0-hour following exercise. The L-glutamine supplementation could increase homocysteine and glucose concentrations during post-exercise recovery period, but there is insufficient evidence to support the view that plasma NO levels are being increased by L-glutamine supplementation after endurance exercise. In conclusion, acute ingestion of L-glutamine does not increase the NO synthesis and does not improve the cardiovascular risk factors during 2 hours recovery period following endurance exercise.
以文找文
期刊論文
1.
Scheuer, J.、Tipton, C. M.(1977)。Cardiovascular adaptations to physical training。Annual Review of Physiology,39,221-251。
2.
Temple, M. E.、Luzier, A. B.、Kazierad, D. J.(2000)。Homocysteine as a risk factor for atherosclerosis。Annals of Pharmacotherapy,34(1),57-65。
3.
Selhub, J.(1999)。Homocysteine metabolism。Annual Review of Nutrition,19,217-246。
4.
Wernerman, J.(2008)。Clinical use of glutamine supplementation。The Journal of Nutrition,138(10),2040-2044。
5.
Stone, M. L.(1998)。Nitric oxide and cardiovascular disease。Current Research of Vascular Diseases,3,226-233。
6.
Walsh, N. P.、Blannin, A. K.、Robson, P. J.、Gleeson, M.(1998)。Glutamine, exercise and immune function: Links and possible mechanisms。Sports Medicine,26(3),177-191。
7.
Dill, D. B.、Costill, D. L.(1974)。Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration。Journal of Applied Physiology,37(2),247-248。
8.
Bowles, D. K.、Woodman, C. R.、Laughlin, M. H.(2000)。Coronary smooth muscle and endothelial adaptations to exercise training。Exercise & Sport Sciences Reviews,28(2),57-62。
9.
Bowtell, J. L.、Gelly, K.、Jackman, M. L.、Patel, A.、Simeoni, M.、Rennie, M. J.(1999)。Effect of oral glutamine on whole body carbohydrate storage during recovery from exhaustive exercise。Journal of Applied Physiology,86(6),1770-1777。
10.
Durstine, J. L.、Grandjean, P. W.、Davis, P. G.、Ferguson, M. A.、Alderson, N. L.、Dubose, K. D.(2001)。Blood lipid and lipoprotein adaptations to exercise。Sports Medicine,31(15),1033-1062。
11.
Green, L. C.、Wagner, D. A.、Glogowski, J.、Skipper, P. L.、Wishnok, J. S.、Tannenbaum, S. R.(1982)。Analysis of nitrate, nitrite, and [15N]-nitrate in biological fluids。Analytical Biochemistry,126(1),131-138。
12.
Hankey, G. J.、Eikelboom, J. W.(1999)。Homocysteine and vascular disease。The Lancet,354(9176),407-413。
13.
Huynh, N. N.、Chin-Dusting, J.(2006)。Amino acids, arginase and nitric oxide in vascular health。Clinical and Experimental Pharmacology and Physiology,33(1/2),1-8。
14.
Kraus, R. M.(1989)。Exercise, lipoproteins, and coronary artery disease。Circulation,79(5),1143-1145。
15.
Mansour, A.、Mohajeri-Tehrani, M. R.、Qorbani, M.、Heshmat, R.、Larijani, B.、Hosseini, S.(2015)。Effect of glutamine supplementation on cardiovascular risk factors in patients with type 2 diabetes。Nutrition,31(1),119-126。
16.
Moncada, S.(1997)。Nitric oxide in the vasculature: Physiology and pathophysiology。Annals of the New York Academy of Sciences,811,60-69。
17.
Newsholme, P.(2001)。Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?。The Journal of Nutrition,131(9),2515S-2522S。
18.
van Hall, G.、Saris, W. H. M.、van de Schoor, P. A. I.、Wagenmakers, A. J. M.(2000)。The effect of free glutamine and peptide ingestion on the rate of muscle glycogen resynthesis in man。International Journal of Sports Medicine,21(1),25-30。
19.
Yang, D.、Brunengraber, H.(2000)。Glutamate, a window on liver intermediary。The Journal of Nutrition,130(4),991-994。
20.
Young, V. R.、Ajami, A. M.(2001)。Glutamine: The emperor or his clothes?。The Journal of Nutrition,131(9),2449-2459。
圖書
1.
Mathews, C. K.、Holde, K. E. V.(1990)。Biochemistry。Benjamin/Cummings。
2.
Gropper, S. S.、Smith, J. L.、Groff, J. L.(2004)。Advanced nutrition and human metabolism。Belmont, CA:Thomson Wadsworth。
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