Christianity, in the forms of Catholicism and Protestantism, has not only reached China and various Chinese communities at different periods, but is also based on different forms of missionary background and ideology. Since the Reformation 500 years ago gave birth to Protestantism, the movement has diversified in various ways in the Western world. In Chinese Christianity, these diversifications have often become standoff points in comparative discourse regarding the differences between Catholicism and Protestantism. Chinese Protestantism has inevitably devised its own unique interpretation and practice in regard to biblical exegeses, catechism, and doctrine. Hence, the discourse of comparison between Catholicism and Protestantism often focuses on their sharp deviations instead of what they hold in common. In addition, such deviations sometimes even cause internal splits and persecution within the Protestant community itself. Therefore, in order to facilitate further conducive discussion of the topic of ecumenical issues, it is necessary to pinpoint and clarify some of the deep underlying misconceptions and twisted arguments in regard to this subject. Hence, this article discusses the important writings, representative figures, and events concerning: 1. Catholicism: ecumenism and anti-ecumenism with regard to Protestantism; 2. From the World Council of Churches to Bible Translation: the epic centers of conflict.