The main purpose of this article is to explore the Han-people's immigration and development of Ere-Chen-Hun River Region in the Dutch Era. Ere-Chen-Hun River in named Ere-Zen River nowadays, it was called Dan-Suei River in the Dutch Era, and even was an important river in the southern area of Taiwan. According to the record in various Kind of documents, Ere-Chen-Hun River Region is also the earliest one that Han-people of Taiwan in immigrated. In this article, first, I try to base on the documents during the Dutch in Taiwan, to explore the background of Han people's immigration and development, and then, to describe the process by way of the field study, oral data, generation chart, and the ancestor spirit tablet and so on.