As researches into population genetic data and the construction of population-based genetic databases have gained increasing attention, it is incumbent on us to contemplate whether these expensive, manpower-consuming population-based genetic databases are under the protection of the IPR laws. Should special right mechanism be established to protect the databases? How to adjust between the authorization strategies and the information access right of population-based genetic databases? We think that the considerable use value and potential commercial benefits of the population-based genetic database often do not satisfy the requirements of originality by the IPR laws. This issue has aroused public attention since the 1991 verdict of the Feist Publication, Inc. v. Rural Telephone Service Co. case by the Supreme Court of the United States, and has incurred much legislative advice by the American Senate and the naissance of the EU database protection order. Hence, both the EU protective system of the special rights of database and the legislative draft of the database laws proposed for times by the American Senate have recognized the results of massive capital or other investments as the object of protection by the database special rights, in order to encourage private investments. Whereas, as population-based genetic database is characterized by both qualities of basic research infrastructure and high time-effiency, investiture with special protective rights is prone to constitute barriers to scienfic studies and considered liable to obstruct the development of sciences. Besides, since most of the population-based genetic databases under construction by the international communities and Taiwan are government subsidized technological projects, the function of "encouraging private investments" in database by the special right mechanism is constrained. Therefore, the question whether it is necessary to employ special right protection to provide incentive for private investments in scientific studs remains doubtful. Consequently, we should investigate into issues on authorization strtegies of population-based genetic database, access rights of genetic database, and questions of reward and benefit-sharing of research outcomes to provide references for the succeeding legislative policy in Taiwan.