The purpose of this research was to understand the current situation and explored the related factors about student nurses' knowledge, attitude, and behavioral intention toward acupressure. The survey was conducted by using questionnaires; the subjects were from senior nursing students of one Nursing Technology College located in Central Taiwan. According to cluster sampling numbers, there were 191 valid questionnaires and the return rate was 90%, the researching results were as followed: 1. 64.9% student nurses had practical experience in acupressure treatment, and most of them acquired such knowledge through school palliative nursing courses; 2. The average correctness rate of acupressure knowledge was 70%; 3. On acupressure portion, 98.6% student nurses had positive attitude and the acupressure method should be promoted; 98.4% student nurses toward acupressure showed acupressure was healthful; 74.4% student nurses agreed with its curative effect; 77.5% student nurses, however, disagreed with its scientific application, and 72.2% student nurses recognized that the acupressure operation was not easy; 4. Over 90% student nurses were willing to accept or execute acupressure treatment; 5. The study showed that attitude was influenced by health consciousness and individual experience, and the individual experience had effect on behavior; 6. The relationship between knowledge and attitude, and between attitude and behavioral intention were positive, but there was no obvious connection between knowledge and behavioral intention. According to the results, both practical training and physical research on acupressure education are suggested.