The mechanism to realize the value of intellectual property mainly vests in contribution of intellectual property as equity, standardization alliances, technology license and transfer, sales and assignment, and infringement lawsuits. Among all, contribution of intellectual property as equity in new venture, joint venture and merger & acquisition can give rise to the best performance, while at the same time, can be risky. Despite the significant consequence, few seem to be familiarized with and take good charge of contribution of intellectual property as equity; be it an enterprise, non-profitable organization or an individual, or be it in theory or practice. This article will depict on major objects related to contribution of intellectual property as equity; such as, the effects of and environment for contribution of intellectual property as equity, the control in contribution of intellectual property as equity and new venture, the key for banks in intellectual property collateral-based financing, the assessment by venture capitalist in new venture, the exit of a new venture through merger and acquisition, the disposal of intellectual property upon winding and liquidation, and the meaning and operation of intellectual property in international investment. It is hoped that the foregoing discussion will help lead to the corresponding development in system, mechanism and professional service to law, finance, accounting, taxation, valuation, banking and investment for contribution of intellectual property as equity, and help create the mechanism and better profitable models for intellectual innovation and entrepreneurship.