α-andβ-arbutin are two whiting components of cosmetic. Hydroquinone(HQ) was detected by GC-MS when theα-and β-arbutin was dissolved in water. The photolysis induced theα-and β-arbutin to form HQ quickly. Because of the cytotoxicity of the HQ, the OCtyl p-methoxycinnamte(OMC) was used to inhibit the potolysis of theα-and β-arbutin and to compare the difference within dark and light. The result was confirmed: the addition of OMC will decrease the formation of HQ fromα- and β-arbutin by photolysis. The by-product methoxycinnamic acid was formed unexpectedly.