In the prevalence of SARS, due to being short of Filtering-Facepiece Respirators, someone had suggested to reuse masks which are disinfected. Though the suggestion goes against the concept of disposability, while in the emergency of epidemic situation and limited resource, the suggestion may be accepted as an emergency measure. This study evaluate the possibility of masks reused by effective disinfection methods without destroying the capture efficiency. And the conclusion can be a reference for short of epidemic prevention materials. Six kinds of respirators loaded Escherichia coli are disinfected by dry heat, wet heat, autoclave, UV light and 75% alcohol to confirm the effective disinfection condition. And the influence of capture efficiency is observed after respirators are disinfected by five different effective conditions. The five effective disinfection conditions are as below: 70℃ oven by 30 minutes; electric pot (96℃) by 15 minutes; 121℃, 1 kg/cm2 by 15 miniutes; 254 nm, 303 µW/cm2 UV light by 30 seconds; and 75% alcohol spraying entirely on the respirator. As to the capture efficiency, four kinds of respirators are under 95% after being disinfected by 75% alcohol, and one kind of respirators is under 95% after being disinfected by wet hot and autoclave, and autoclave also makes five kinds of respirators to change shape. Dry hot and UV light disinfection methods hardly affect the capture efficiency of respirators. Though the five disinfection methods can kill Escherichia coli on the respirators, it is not suggested to reuse Filtering-Facepiece Respirators in peacetime. Only if respirators have to be reused inevitably, it is suggested to reuse respirators disinfected by dry hot and UV light.