This study took the “Journey of Printing Collections Exhibition” at the NSTM as an example to explore how museum collections were used to interpret their values and meanings for helping visitors to understand their multiple meanings. Firstly, the curatorial ideas and designs of the exhibition and selection of printing collections were described. Besides, marketing strategies and public relations were applied to promote the exhibition. Finally, a survey was conducted to analyse whether visitors knew the conveyed information and curatorial ideas of the exhibition. And beneficial results were also evaluated to see whether by systematic planning, selection, and interpretation of the print collections, visitors can know more about the printing collections of NSTM. The conclusions were described as followed: 1. There were positive and significant results from the curatorial ideas and marketing strategies proposed in the initial stage of the exhibition. Through storylines and systematic selection of collections, visitors can have basic understanding for the printing industry. 2. There were 84 NSTM collections and 50 artifacts borrowed from other museums in this exhibition. The communication for scientific significance and technology was achieved through collection interpretations. The survey showed that the major reason to visit the exhibition was “their interests in subjects related to printing designs.” Clearly, the collections attracted visitors to the Museum. 3. More than half of the interviewees indicated that the contents of this exhibition were moderate, and 50% of the interviewees believed that they partly understood the scientific significance of this exhibition; 60% of the interviewees thought that this exhibition was helpful in promoting popular science education. The results revealed that the exhibition of the printing collections held by NSTM was meaningful in attracting visitors and advancing their understanding of the exhibition contents.