Promoting teacher professional development is the core strategy and pathway to improve the quality of teacher education. Using the TALIS data, this paper focuses on analyzing the professional development of teachers in 36 countries and regions participating in TALIS. The study found that teacher’s gender, work experience and educational background, as well as the demand for professional development, had significant influences on teachers’ participation in professional development activities. Shapley value decomposition results show that cooperative culture of teachers contributes to the largest effectiveness on teachers’ professional development. Thus, the policy makers and implementers should focus on meeting the needs of teacher development. Based on the courses and workshops, teachers should be encouraged to establish peer collaboration and collective teaching. Policy makers should construct long-term incentive mechanism for teacher professional development.