The advancement of information and medical technology has contributed to the increased amount of medical waste at an alarming rate. Medical waste handled inappropriately could pose serious threat to workers who are in charge of disposing medical waste. The present study aims to explore the perception of medical waste among students of Health Care Administration as well as factors influencing students’ perception. Surveys were conducted on 650 students of Department of Health Care Administration using structured questionnaires There were 554 valid questionnaires collected, with 86% recovery rate. The results demonstrate that 44.8% of the students are aware of the procedures of medical waste disposal whereas 40.1% of them lack general perception; 63.1% of the students obtain related information through newspaper while only 35.2% of them learn by discussing with instructors. Furthermore, it was found that school systems, year in college (grade), grade-point average, and taking related courses are significantly associated with level of perception. Therefore, it concludes that the school should offer more courses to prepare students with knowledge on 1) medical waste, 2) proper management of medical waste, and 3) application of expertise on duty in order to reduce occupational hazard in career.