Purpose: This study to relate of Professional driver in health-promoting lifestyle, driving and body mass index, that in accordance with professional driver's workplace health promotion programs to enhance healthy living and service quality professional driver. Methods: This study used to cross-sectional of quantitative research design, the research objects are professional driver who work in the regional driving of Kinmen County, by conducting questionnaires of 180 copies. 176 questionnaires were recovered, Deducting 4 copies of invalid questionnaires, and totally we collected 176 copies of valid questionnaires. By using descriptive statistics, chi-square test, one-way ANOVA and Pearson correlation, the between variables was significant differences, we continue to analysis the Scheffe's, the significance level set at α=.05. Results: The impact of the type of driving the vehicle in the health-promoting lifestyle , self-realization and exercise behavior in the two dimensions of health-promoting lifestyle index scores were significantly higher than those of large trucks in a taxi (T > LT). Affect the body mass index of health-promoting lifestyle , in the two dimensions of health-promoting lifestyle score indices were significantly higher than in the standard body fat body (SD > OB). Driving a vehicle, body mass index and health promotion of inter- connected lifestyle, the standard size and health responsibilities (r=.24, p < .05), motor behavior (r=.28, p < .05) and buses (r=.26, p < .05), health responsibility and exercise behavior (r=.25, p < .05) and exercise behavior and nutrition the behavior of a significant positive correlation (r=.26, p < .05) between. Conclusion: The professional driver driving the vehicle, body mass index and health-promoting lifestyle changes among items connected with part of standard body of professional drivers can better attention to health promoting lifestyle (health responsibility and exercise behavior), and the bus driver to drive a vehicle compared to other types of more attention to their body and maintain good physical and mental condition, in order to enhance bus service quality.