The purpose of this study was to compare the knowledge, attitude and preventive behaviors about pulmonary tuberculosis for tuberculosis patients and non-tuberculosis patients and to investigate patients?knowledge resources, motivations to search the knowledge, and the needs of patients. The results could help to set up health education strategies for the public. This research was based on the eighth survey of tuberculosis prevalence in Taiwan. Three groups of subjects were recruited. Group I consisted of 43 subjects who had been diagnosed to have tuberculosis and had received treatment. In this research, they were labeled as old-tuberculosis patients. Group II consisted of 100 subjects who hadn't any treatment and were labeled as new-tuberculosis patients. Group III consisted of 143 subjects without abnormal chest films. Data were collected by questionnaires . Major results are shown as below: 1. The old-tuberculosis patients' knowledge of tuberculosis was at medium-low level. Their knowledge of tuberculosis prognosis was good overall but the study revealed some misconceptions about nursing care of tuberculosis. New-tuberculosis and non-tuberculosis patients?knowledge of tuberculosis is at medium level. But their knowledge of transmission of tuberculosis was poor. 2. The significant predictors of the knowledge of tuberculosis scores in the old-tuberculosis patients?group were their knowledge comes from health team members? in non-tuberculosis patients were 烠hey hear about tuberculosis?and 浵ope to get tuberculosis knowledge? 3. All three groups showed positive attitude. But they reported low attitude scores in prevention of tuberculosis is the duty of the public? 4. The most influential factor of attitude for old-tuberculosis patients was knowledge scores, and for non-tuberculosis patients were knowledge scores and hope to get tuberculosis knowledge. In new-tuberculosis patients and non-tuberculosis patients, knowledge scores were found to be significantly related to regular chest X-ray check up. Chest X-ray was one of the important screening tests for tuberculosis. Based on the finding in this research, we can improve participation in regular chest X-ray check up through health education program to improve their tuberculosis knowledge.