Due to the regional economic integration of ACFTA, TPP which the United States is expected construct may play the leading role in the economic integration in the Asia-Pacific region in the future. TPP may become the platform of the international trade rules in a new generation. Focusing on trade liberalization and the rules of environmental protection, labor and intellectual property rights, TPP is the most powerful FTA and it is highly possible that TPP can be the mode of the future trade agreementsIn 2010, the TPP members' GDP was 2.1 trillion US Dollars which were approximately 35% of the world trade and higher than European Union GDP. TPP is the largest global regional economic organization which achieves up to 42% of the import market share of Taiwan. Taiwan may enhance the economic position by joining TPP. In addition, TPP is an open agreement which is mainly constituted of Asia-Pacific Economic Cooperation (APEC). Therefore, it is legitimacy and legality for Taiwan to apply for being a member of ITT. Moreover, the internal industries of Taiwan have the urgency to evaluate the effect carefully and reduce the negative impact on the participation of TPP.