Qian Mu was a prolific scholar. His works could be piled up as high as himself. Almost all his works focused on the statement and propagation of Chinese culture and history. From his academic viewpoint, his works were mainly on traditional Confucianism and he was particular about concrete evidences filled with his own opinions. He was called the first class academic in contemporary China. He really deserved this reputation. Although Qian Mu’s thought was advanced, there was no denying that he was formalistic. This paper is to study Qian Mu’s concepts of spirit and immortality. I found that Qian Mu studied the spiritual thoughts of Western philosophies and religions based on his attitude of managing documents and records. Under the guidance of his introduction that the performance of Western ethics was not better than that of Eastern ethics, he said that the spiritual thought was merely an imagination. He discussed religious problems through academy, especially objective documents and records. Under the circumstances, the spiritual concepts between philosophy and religion would be two parallel roads which could not intersect in the end. It’s a pity. On the other hand, Qian Mu’s concept of immortality came from a Chinese traditional classic, Zuo Commentary. The so-called three forms of immortality in character, words and deeds have been Chinese traditional thoughts. Under his statement and comment, the meaning of these thoughts became more plentiful and evidential. There would be deep effect of positive guidance and encouragement on modern readers. This was one of Qian Mu’s contributions to academic thought.