"The Mysterious Case of Qing Zhu Si", also known as "An-Khe Mysterious Case", was one of the four most well-known odd cases in Taiwan, which has been popular in Taiwan in the form of Taiwanese ballad booklet since the early period of Japanese rule. It is still frequently seen in Taiwanese operas and Hakka operas nowadays. After comparing this story with the "General Records of An-Khe County", it was confirmed that such opera considerably coincided with "The Mysterious Case of Qing Zhu Si". Not only did the County Magistrate Huang Chai-chung really exist, but he also served as the An-Khe County Magistrate as well as was closely associated with An-Khe Cheng Huang city god, thereby inferring that the relevant settings of this play must have been well founded. It is not yet possible to confirm whether or not that this story actually happened; further, it was found that "The Mysterious Case of Qing Zhu Si" actually showed an extremely high degree of similarity to "Eyes on the Roof" and "Fifteen Strings of Cash" in terms of plot weaving after probing into the dramas of the Qing Dynasty, thus people cannot help suspecting the relationship among them. After all, is "The Mysterious Case of Qing Zhu Si" an original creation, adaptation or patchwork? Such issue remains unsolved as well as depending upon more evidence.