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題名:孤獨症譜系障礙者的視覺-空間工作記憶缺陷及腦機制
書刊名:心理科學進展
作者:李松澤胡金生李騁詩王琦劉淑清康曉東崔麗
作者(外文):Li, SongzeHu, JinshengLi, ChengshiWang, QiLiu, ShuqingKang, XiaodongCui, Li
出版日期:2016
卷期:2016(7)
頁次:1050-1064
主題關鍵詞:孤獨症譜系障礙視覺-空間工作記憶認知加工腦功能腦結構Atism spectrum disorderVisual-spatial working memoryCognitive processingBrain functionBrain structure
原始連結:連回原系統網址new window
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孤獨症譜系障礙(ASD)個體存在視覺-空間工作記憶加工缺陷,主要表現在4個方面,即隨認知負荷增大而缺陷加重、工作記憶容量不足、工作記憶加工過程中的注意功能失調和對刺激進行整體組織的能力缺乏。神經機制研究顯示,ASD個體存在明顯的額-頂工作記憶網絡激活異常,以及相關腦區的腦結構、白質連接異常。另外,作為基礎性的認知加工過程,ASD個體的視覺-空間工作記憶各加工環節與言語工作記憶、執行功能、社會認知等因素均存在交互影響。縱觀目前研究成果,未來研究可從研究手段、機制探究和干預訓練三方面入手,著眼於研究方法的生態化和多元化,揭示客體和空間工作記憶的機制分離,並著力開發更具針對性的干預訓練模式。
Autism spectrum disorder(ASD) is confirmed to be impaired in visual-spatial working memory,mainly characterized by effects of cognitive load and capacity limitation.Recently,the functions of attention and central coherence in ASD through visual-spatial working memory performance started to be concerned.Neuroimaging studies have showed functional and structural brain abnormalities in frontoparietal working memory networks in ASD,which are generally linked to frontal-lobe dysfunction.In addition,studies also involved in relations between visual-spatial working memory and other cognitive processes,such as verbal working memory,executive functions and social cognition.From wide view of previous researches,future studies should put ecological validity of experimental tasks on the important status,take full advantage of neuroimaging techniques and longitudinal studies,further reveal the mechanism separation of object and spatial working memory in ASD,and devote to develop an effective intervention training mode.
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