This article reveals the problem of publicness during the establishment of ethical oversight of human research in Taiwan. Through examining the development of anthropological codes of ethics in the United States and Taiwan, we come to understand the particular concerns of anthropology in these two societies, and that insight helps us reckon with the significance and constraints of institutionalizing research ethical oversight. Anthropology generally reminds scholars of their individual responsibility to grapple with ethical challenges in the context of cultural difference and social change. Constantly reflecting on the disciplinary cores, understanding the subaltern, and remaining sensitive to cultural difference constitute the fundamental ethical guidance of anthropology. Anthropological code of ethics should become the essence when making the discussion on research ethics public.