Chinese intellectual Su Shi had a profound understanding and self-awareness of disease, medicine, and health promotion techniques. Su was relegated to Huangzhou in his middle age. The event was a key setback in his life. In addition to the reversal in his career development and sudden poverty in life, Su also faced the predicament of disease, and he was bedridden for several months, during which time he stayed at home and reflected on his life. Moreover, unemployment and disease prompted him to actively engage in health-promoting practices. Su proposed restraint on diet and desires. In addition to health-promoting diets, Su emphasized maintaining psychological tranquility by regulating qi (literally breath). He also compiled the "Knacks of Health-Promoting Practices," integrating ancient health-promoting regiments such as tooth knocking, gargling with saliva, breath holding, vipassana meditation, and massaging. These simple and feasible health-promoting techniques concluded Su's health-promoting practices in his middle age. In the midst of hardship in Huangzhou, Su managed to transcend his life's difficulties of relegated and disease to develop an open-minded liberal attitude, which inspired numerous intellectuals in later periods and triggered the trend of health-promoting practices among intellectuals since the Song dynasty.