The students with cerebral palsy could not participate in E-learning with general methods for their limitations of physical control. Although there are many adaptive computer devices available recently, how to select appropriate devices for the client is still difficult for clinical intervention. This study try to set up a two steps pointer selecting procedure based on single subject alternating treatment design. A client with cerebral palsy was recruited to test the procedure. The authors adopted assessment tools to evaluate the client's performance by using candidate devices in various interaction environments. The accuracy, movement time, and ratio of path length to task axis length (PL/TA) served as dependent variable. The results of the case study indicated that the procedure of collecting the performance data systematically could assist the clinical professional to select appropriate pointer and interaction environment for the client with cerebral palsy.