The umbilical cord blood contains plentiful hematopoietic stem cell, it is the main source of immune system and human body's hematopoiesis, and it can take the place of marrow in medical treating purposes. The first successful transplant operation of umbilical cord blood in the world in 1988 led to a series of umbilical cord blood-related research and development. In spite of it is over 20 years from the first successful transplant operation of umbilical cord blood, the umbilical cord blood related seem still an emerging medical industry with uncertainty. Researches about umbilical cord blood are still new issues, and most previous researches of them are medical related, few of them concern with management. In this study, we use the theory of planned behavior (TPB) to explore peoples' cognition and behavioral intention toward umbilical cord blood, we also use the uncertainty of umbilical cord blood as interference information to study whether the peoples' behavior intention will be changed as they contact these information. This study concludes that: (1) When the level of individual's manner, subjective norm and perceived behavioral control in denoting umbilical cord blood are high, the behavior intention of denoting umbilical cord blood is raised; and when the level of individual's manner, subjective norm and perceived behavioral control tend to privately store umbilical cord blood, the behavior intention of privately storing umbilical cord blood is easier generated. (2) After contact the interference information, people increase their behavior intention in donating umbilical cord blood, and the behavior intention of privately storing umbilical cord blood is tend to weaken. (3) The general public will be subject to the interference information to raise their behavior intention in donating umbilical cord blood; while the prospective parents' behavior intention in donating umbilical cord blood are not affected by the interference information.