Social workers in rural areas often live and work in the communities that they serve. Therefore, they may develop dual/multiple relationships with service users. This raises some complex issues about how social workers in rural areas set their professional boundaries. Besides the characteristics of rural areas, special perspectives on interpersonal relationships in Chinese culture as well as collectivism in indigenous tribes also deepen the complexity of professional boundary setting. This paper discusses the notion of professional boundary, related practice issues in rural areas, and the contextual factors affecting professional boundaries. Lastly, suggestions on boundary setting will be presented.