The purposes of this research were to explore the relations among health lifestyle, knowledge, attitude and behavior of the populace and tourist, as well as potential demands in hot spring wellness tourism. Furthermore, they could help the government and dealers to make the right healthy-tourism strategies. This research was undertaken via structural formula questionnaire. There're 600 samples were finished both from Taipei Beitou hot spring areas and Taichung Dakeng hot spring areas. They were divided into "have taken hot spring bath before" and "have not taken hot spring bath before", further to distinguished their lifestyle types into active healthy lifestyle and passive healthy lifestyle by cluster analysis. And t-test, correlation and stepwise regression were used to confirm the relation of their healthy lifestyle, knowledge, attitude and behavior. The results showed that single women, below 30-year-old, who had active healthy lifestyle type, they had more positive knowledge, attitude and behavior in hot spring wellness tourism. People, who had hot spring bath with active healthy lifestyle type, also care about the popularity of hot spring hotels. When people got more healthy lifestyle, they had more knowledge, attitude and behavior in hot spring wellness tourism (p<.05). The knowledge positively related to their attitude, and attitude also positively related to their behavior in hot spring wellness tourism (p<.05). We suggest our government and dealers should develop and promote the market of spring wellness tourism actively. Especially focus on the young single women who had the active health lifestyle type.