Basing on the materials collected in the Hung-ming chi (the Collection of Highlighting), this paper makes a investigation of important events of Chinese Buddhism during the period (184 ∼ 265) from the later Han Dynasty to the Northern and Southern Dynasties. In the paper, the three issues are discussed: the status of the Buddhism in the period of the later Han Dynasty and the Three Kingdoms; Some controversies in the period of the Southern Dynasties; the Buddhist status in the period (317 ∼ 479) of Jin & Song Dynasties. As for Buddhism in the Three-Kingdoms period, this demonstrates that Buddhism has no longer clung to the indigenous beliefs such as Taoism and other worships, yet it had to make its theoretical exegeses with the help of the Xuan-xue (a metaphysics hybridizing Confucian and Taoist teachings). In regard with the controversies concerning Buddhism in the Jin & Song Dynasties period, the paper holds that the materials in the Hung-ming chi'provides us two fundamental issues: one is about the Yi-xa-zhi-bian (How to Make Distinction Between Chinese Tradition and Barbarism) and the Ben-mo-zhi-bian (Whatever is the Root of Chinese Culture); the other one is whether the soul is eternal or not. The former involves the integration of Buddhist culture and inherent culture in China, and eventually leads to the interest in the ontology of the Chinese philosophy; the latter deals with the very a critical presupposition for Buddhism and any religions in their theology. The great controversy in this period finally solved the theoretical problem at least to most the Chinese folk and hardly anyone doubted the soul exists eternally since then. As for the Buddhist status in the same period, three layers can be found among its believers: the emperor and people in his palace; the literati and the folk people in society. The Theoretical form of Buddhism is mainly concerned with both the literati's personal experiences and the social atmosphere they lived in.