The purpose of the study was to investigate the influences of digital reading and instruction on higher-grade students' reading comprehension. The researcher designed both pretest and posttest in the quasi-experiment. The students were from two classes at an elementary school in Kaohsiung City. The experimental group, led by the researcher, had digital reading and instruction twice a week for ten weeks. The control group had their reading instruction as usual. Then, the quantitative data were collected based on the ”tests of reading comprehension of elementary students” by the researcher, and its covariance was analyzed (ANCOVA). Also, the qualitative data, including teacher's observations and students' answers to open-ended questions on the same scale, were analyzed. The study results were as follows:1. There were significant differences of their reading comprehension between the two groups.2. There were no significant differences of their reading interest between the two groups.3. The results of their overall reading comprehension reveal no significant differences, but that in terms of the texts in type of stories reveals significant differences.