With its original generosity, Catholicism has always been a religion of stragification par excellence, spreading Jesus' Gospels to strangers. However, in China, after almost 14 centuries' of effort, Catholicism is still considered as a "foreign religion," as it was when first introduced to China in the 7th Century in the form of Nestorianism. Why? This paper will look for the reasons-why by presenting the ideas and strategies of "strangification" and "self-reflection" on three levels: linguistic, pragmatic and ontological. Then it will move on to examine the major periods of Catholicism in China: Nestorianism in the middle of the first millennium, Matteo Ricci and his Jesuit followers in the middle of the second millennium, and Cardinal Yu Bin and Archbishop Lokuang at the end of the second millennium. With this historical background, we will proceed to characterize the third Millennium as moving from globalization to spacialization, total informatisation, and contrasting secularity with mysticism. At the end, I will give some suggestions as to how to work with the strategy of strangification on the inculturation of the Catholic Church in the third millenium with these characteristics.