This paper discusses the issue of the meaningfulness of human life on three levels: the body, social commitment and spirituality. The concept of the body is highlighted in both phenomenology and Chinese philosophy. While phenomenology makes a distinction between the corps vécu (lived body) and the corps organique (organic body), Chinese philosophy sees them as unified, and this point is corroborated by recent developmental psychology of infants up to teenagers. I take desire to be the original energy in the human search for further meaningfulness. Starting as "desiring desire," then oriented to "desirable desire," and finally concretized as "desired desire," the development of desire takes various forms of representation, first nonverbal, then verbal, and thereby enters into the process of communication in society. In social commitment, it is most important to have what I call "humanist beliefs" in values such as love, justice, truth, good, beauty, harmony …etc. All these are from human nature as human and can be realized as human values. At the end, I ask: does the body play any positive role in human spiritual life or even mystical experience? I take St. John of the Cross and Laozi's "to see the nature of the body in letting the body be itself" to illustrate the idea that the body does play a positive role in mystical experience. Thus, starting from desirable desire, I discuss its further destiny in the construction of representations and societies, transcending all their limits. This process goes well with the development of the human mind/heart. Although it begins with the original generosity of the desiring desire, nevertheless it develops into all kinds of intentionality, which means "to be conscious is to be conscious of," and then develops again into the dialectics of what Maurice Blondel calls "volonté voulante" and "volonté voulue", and then matures in the ethical life of society, and finally completes itself in spirituality and religious life, even in being united with the ultimate reality in mystic experience. This whole process indeed belongs to the same life that always strangifies and transcends itself in order to come up to the level of perfection.