The purpose of this longitudinal study was to investigate the factors contributing to Taiwanese citizens’ visit to science and technology museums in 2008, 2012 and 2015. The samples of this study were selected using probability proportional to size sampling method, and the sample sizes were 2,024, 1,863 and 1,831 adults, for the years of 2008, 2012, and 2015 accordingly. The results demonstrated an increase in the proportions of Taiwanese citizens’ visits to science and technology museums in 2008, 2012 and 2015, from 14.1%, 23.4% to 28.9%, respectively. Especially, there was a significant increase in occasional visitors, younger age group, higher education level, higher income level, residents of northern and remote areas of Taiwan. There was a significant change in factors contributing to visits to science and technology museums. In 2008, the major factors contributing to visits were residential areas and types; in 2012, the major factors were the residential areas, education level, residential types, age level, positive attitudes toward science and income level; and, in 2015, the major factors were the education level, positive attitudes toward science and income level. The research provided implications for the operation of science and technology museums in the future.