The main purpose of the study was to explore the knowledge, attitudes, and behavior of drug abuse, and the needs for drug education among junior high, senior high and vocational high school students in Taiwan area. In addition, the study also predicted these variables by socio-demographic variables, academic involvement, peers' drug abuse behavior and attitudes, and family factors. The sample was selected by the proportionate probability sampling method. Sixty schools were included, with the total number of valid questionnaires being 7,856. The data were collected via a group self-administration in February and March, 1994. The main findings of the study were as followings: 1. The rate of the students who have ever smoked cigarettes, drunk alcohol, and used addictive drugs were above 30%, above 70%, and less than 4%, respectively. 2. The rate of correct answers for the knowledge test of drug abuse among students was above 75%. 3. The most common sources of knowledge of drug abuse among the students were television programs, followed by newspapers and teachers. 4. Most of the students disapproved of durg-using behaviors. 5. Most of the students wanted to learn more about drug education. 6. Among the students, there was a significant correlation between attitudes toward drug abuse and (1) knowledge of drug abuse, and (2) needs for drug education. 7. Among the students, the knowledge of and attitudes toward drug abuse, and the needs for drug education could be predicted by socio-demographic variables, academic involvement, peers' drug-using behavior and attitudes toward drug abuse, and family factors.