Theoretically speaking,the meaning of an object changes constantly,and new knowledge about this object emerges. Different understanding and utilization of this object from different societies have enriched its genealogy. Therefore,the retrospection of the history and the space processes of the object from the current knowledge system are indispensable for the cultural studies of this object. On the basis of historical documents and the first-hand field materials of North Maluku Islands in Indonesia,this article presents the historical course about the formation of clove’s knowledge system through the mobility of Maluku cloves,and analyzes the economic and cultural connection between the clove and different types of societies,especially Southeast Asian islands,ancient China and European society before modern times.