The purpose of this study was to understand the home health care needs of children with cancer from the point of view of the caregivers. 146 caregivers were interviewed using a structured questionnaire from northern Taiwan medical centers and district hospitals. The results showed that: (1) The average age of children with cancer was 10 years old, most were male. (2) The average duration of disease was 4.7 years, most frequent diagnosis among them was leukemia. (3) The knowledge and expectations of most caregivers were very limi-ted, and most of them wanted to know more about home health care for children. Consultant nurses were the ones most caregivers expected to do home visits. In addition to these nurses, social workers, dieticians, teachers, physicians, in this order, were also expected to visit. Over half of the interviewees admitted that the fees for home health care would be a burden. (4) Ten items of home health care needs for cancer children were “mental consultation for children” “prevention and management of accidents” “diet assessment” “emotional support for caregivers” “dietetic guidance” “home teaching” “intravenous injection” “management of breakdown of mucous membrane” “management of fever” and “pain management”