人性論是郭店楚筒儒家典籍研究中備受重視的一個課題，論著已不勝枚舉，但一些基本概念，如「天」、「命」、「性」、「情」的地位、性質、作用等還有待進一步梳理。郭店楚簡認為「命」、「性」屬於「本」的領域，為「天」所生，但「命」、「性」並非道德本體。「情」屬於「化」的領域，為「人」所生。「天」與「人」相分、「本」與「化」相對的思維構造，對「性」自然而然一面的強調，對「命」之無常的認識，用生成模式排列前後秩序的表述方式，和《淮南子》等道家文獻的多處相似，均表明郭店楚簡儒家文獻和道家有密切關係。先秦秦漢儒家中，與郭店楚簡思路接近者是荀子， 而不是孟子。

The theory of human nature in the Guodian Chu Slips which is thought to be the confucianist history document has received much attention and the researches have been too numerous to mention. While, the basic conceptions, such as, "Tian," "Ming," "Xing," and "Qing" still need further studies. From the Guodian Chu Slips, the conception of "Ming" and "Xing" belongs to the "Ben"(basic) field, which is born by the "Tian." But the conception of "Ming" and "Xing" is not a moral ontology "Qing" is born by the "Ren"(human being), belonging to the "Hua"(change) field. The Construction of the separation "Tian" and "Ren", the relation between the "Ben" and "Hua," the Emphasizing the naturally quality of "Xing," the understanding of the uncertainty of "Ming", all these are similar to the history documents of the Taoism. It shows that the Guodian Chu Slips has a close relation to the Taoism. It is the thoughts of Xun Zi that is more familiar to the Guodian Chu Slips, not the Mencius, in the pre-Qing period, as well as the Qin and Han dynasty.